Welcome to the CORKA Trial website. As a potential participant you can find out information about the trial and how to take part. As a participating site you can see the latest news, Recruitment figures and download trial documents and CRFs. The CORKA study was developed in response to a commissioned call by the National Institute for Health Research (NIHR) Health Technology Assessment (HTA) programme for research into a functional home based rehabilitation programme for patients who may be at risk of poor outcome after knee replacement. Participants will be randomised to one of two arms, ‘home-based rehabilitation’ or ‘Usual Care’. Those in the usual care arm will receive a minimum of 1 and a maximum of 6 sessions of physiotherapy as delivered locally, e.g. class, one to one, etc. Those in the intervention arm will receive 7 sessions of a functional rehabilitation programme over a 12 week timescale. The intervention will be delivered using physiotherapists and physiotherapy assistants in the participants’ home. Participants will be followed up at 6 months and 12 months.
Chief Investigator - Associate Professor Karen Barker
Trial Manager - Nicola Kenealy
Research Physiotherapist/ PI at Nuffield Orthopaedic Centre - Jon Room
The Primary objective for the CORKA trial is:
- To compare the patient reported functional outcome and quality of life of the CORKA trial rehabilitation protocol versus standard care in participants at risk of poor outcome after knee replacement.
Secondary objectives for the CORKA trial are:
- To assess the safety and serious adverse events associated with the treatment programme
- To assess the acceptability to the treatment programme for patients and therapists through both a RCT and a nested qualitative study
- To assess the cost effectiveness of the different treatment strategies
The following outcome measures will be collected at baseline, 6 months and 12 months
- Late Life Function and Disability Instrument (LLFDI)
- Oxford Knee Score
- Physical Activity Scale for the Elderly (PASE)
- EQ-5D
- KOOS
- Functional Co-morbidities Index
- Physical measures :– 30 sec Chair Stand test, Figure of 8 test, Single leg stance
- Participant diaries – exercise, medication, use of healthcare services, falls (time to first fall), adverse events
The CORKA trial has now been published. Plesae click on https://pubmed.ncbi.nlm.nih.gov/33250068/ to access the full article.
